Mastocytosis

Nature Reviews Disease Primers, Published online: 24 April 2025; doi:10.1038/s41572-025-00611-8
Mastocytosis is characterized by focal accumulations of clonal mast cells in the skin and/or in internal organs such as bone marrow, spleen, lymph nodes or the gastrointestinal tract. In this Primer, Akin et al. discuss the epidemiology, pathophysiology, diagnosis and current management of mastocytosis, and future research areas.