Differences of sex development
Nature Reviews Disease Primers, Published online: 31 July 2025; doi:10.1038/s41572-025-00637-y
Differences of sex development (DSD) encompass a group of rare congenital conditions characterized by atypical sex development. In this Primer, Flück and colleagues provide insights into our current understanding of rare DSD pathophysiology, its prevalence and diagnosis as well as challenges and controversies related to clinical management.













