Acute rheumatic fever and rheumatic heart disease
Nature Reviews Disease Primers, Published online: 26 February 2026; doi:10.1038/s41572-026-00685-y
In this Primer, Zühlke and colleagues review the epidemiology, pathophysiology, diagnosis, management and quality of life of individuals with acute rheumatic fever and rheumatic heart disease, which are autoimmune sequelae of group A Streptococcus infection.













