New “super antibiotic” stops deadly gut infection without destroying the microbiome

A newly developed antibiotic called EVG7 could offer a powerful new way to stop Clostridioides difficile, a dangerous gut bacterium that often returns after treatment. In mouse studies, researchers found that even a very small dose of EVG7 was highly effective at clearing the infection and preventing it from coming back. Unlike many current antibiotics, which wipe out large portions of the gut microbiome, EVG7 appears to spare beneficial bacteria that naturally help keep C. difficile in check.