Human mini guts reveal new insights into the process leading to Cronkhite-Canada syndrome and potential new therapies

Researchers working with human intestinal organoids, also called mini guts, have shed new light on the potential causes of Cronkhite-Canada syndrome, a rare condition characterized by abundant non-cancerous growths or polyps in the intestine and other symptoms. They show a connection between high polyp proliferation and increased levels of serotonin produced by the intestinal epithelium.