Osteoarthritis
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Nature Reviews Disease Primers, Published online: 13 February 2025; doi:10.1038/s41572-025-00594-6
Osteoarthritis is a complex, multifactorial disorder affecting the entire joint that can cause pain and is a leading cause of disability and premature work loss. In this Primer, Tang and colleagues summarize the epidemiology, pathophysiology, diagnosis and management of osteoarthritis and highlight the global burden of the disease.