Systemic capillary leak syndrome
Nature Reviews Disease Primers, Published online: 14 November 2024; doi:10.1038/s41572-024-00571-5
Systemic capillary leak syndrome occurs when there is systemically dysregulated fluid homeostasis. This can lead to hypotensive shock, widespread tissue oedema and multi-organ dysfunction syndrome. In this Primer, Druey and colleagues summarize the epidemiology, pathophysiology, diagnosis and management of this condition.