Tumour lysis syndrome
Nature Reviews Disease Primers, Published online: 22 August 2024; doi:10.1038/s41572-024-00542-w
Tumour lysis syndrome (TLS) is an oncological emergency characterized by extensive tumour cell breakdown, leading to the rapid release of intracellular contents into the systemic circulation. In this Primer, Howard and colleagues summarize the epidemiology, pathophysiology, diagnosis and management of TLS.