Biodegradable gel shows promise for cartilage regeneration

A gel that combines both stiffness and toughness is a step forward in the bid to create biodegradable implants for joint injuries, according to new research. Mimicking articular cartilage, found in our knee and hip joints, is challenging. This cartilage is key to smooth joint movement, and damage to it can cause pain, reduce function, and lead to arthritis. One potential solution is to implant artificial scaffolds made of proteins that help the cartilage regenerate itself as the scaffold biodegrades. How well the cartilage regenerates is linked to how well a scaffold can mimic the biological properties of cartilage, and to date, researchers have struggled to combine the seemingly incompatible properties of stiffness and toughness. Now, new research outlines a method to marry these properties in a biodegradable gel.