How mitochondria drive autophagy
A new study unravels the relationship between mitofusins (mitochondrial proteins) and autophagy. Using gene editing with CRISPR-Cas9, the team has been able to study these proteins without altering them or producing them in excess, thereby allowing observation of their true function. The research paves the way for the development of therapeutic strategies to regulate autophagy, address metabolic diseases, and promote healthy aging.
