Schizophrenia
Nature Reviews Disease Primers, Published online: 27 November 2025; doi:10.1038/s41572-025-00667-6
Schizophrenia is a complex and often long-lasting mental health condition that typically begins in late adolescence. In this Primer, Leucht and colleagues review the epidemiology of schizophrenia and current understanding of its pathophysiology, diagnosis and treatment, and discuss the quality of life of affected individuals as well as future research directions.













